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Histopathology

Histopathology is the study of diseases at a microscopic level, examining tissues and cells to understand the structural and functional changes that occur due to disease processes.

Meiji Techno Microscopes are essential tools in histopathology, the branch of pathology that involves studying tissues to diagnose disease. Here’s how they’re used:

 Main Uses of Microscopes in Histopathology

  1. Meiji Techno MT Series Biological Compound Microscopes are used for Tissue Diagnosis
  • Light Microscopes are used to examine thin tissue sections stained with dyes (like H&E – hematoxylin and eosin).
  • Pathologists study cell structure, tissue architecture, and identify abnormalities like cancer, inflammation, or necrosis.
  1. Staining Analysis
  • Different stains highlight specific tissue components:
    • H&E: general tissue structure
    • PAS: carbohydrates/mucins
    • Immunohistochemistry (IHC): identifies specific proteins using antibody markers
  • Microscopes help visualize how these stains bind to tissue, helping to classify diseases at a molecular level.
  1. Tumor Grading and Staging
  • Meiji Techno Microscopes allow precise assessment of tumor size, cell type, mitotic rate, and invasion depth, guiding cancer staging and treatment plans.
  1. Infectious Disease Detection
  • Microorganisms like bacteria, fungi, or parasites can be directly seen in tissues using special stains (e.g., Ziehl–Neelsen for TB).
  • Important for diagnosing infections like tuberculosis, histoplasmosis, or malaria.
  1. Digital Pathology & Telepathology – HDMI , USB 3.0 Cameras are available as a optional add on to all Meiji Techno Trinocular Models
  • Digital microscopes scan whole slides to create high-res images that can be viewed on a screen.
  • Enables remote diagnosis, AI-assisted image analysis, and case sharing for education or consultation.

 Educational Case Study Example

Case: Diagnosing Breast Cancer

  • A biopsy sample from a patient’s breast lump is processed and stained.
  • Under the microscope, a pathologist identifies malignant ductal cells and uses IHC staining to check for estrogen receptors.
  • Based on the microscopic features and marker expression, the tumor is classified, which guides treatment (e.g., hormone therapy).

 Types of Microscopes Commonly Used

  • Compound Light Microscope – routine tissue slide examination. Meiji Techno MT4000, MT5000 Series
  • Fluorescence Microscope – for IHC and molecular markers ) Meiji Techno MT6000 Series
  • Electron Microscope – rare, but used for ultra-structural detail (e.g., kidney biopsies) ( Meiji Techno does not have anything for this category)

Histopathology

LIFE SCIENCE

The following item requires an illumination:
EMZ-5 + MA502 + P Stand

  • EMZ-5 + MA502 + P, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-5 + MA502 + PKL-2, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-13 + MA502 + PLS-2, Stereo Zoom Binocular Stand Configuration System, Magnification (10X – 70X), W.D. 90mm (3.54″)

  • CZ-1105 1X CMO Binocular Zoom Stereo System, Working Distance 78mm

  • CZ-1105TR 1X CMO Trinocular Zoom Stereo System, Working Distance 78mm

  • CZ-1100 1X CMO Ergonomic Binocular Zoom Stereo System, Working Distance 78mm

  • CZ-1100TR 1X CMO Ergonomic Trinocular Zoom Stereo System, Working Distance 78mm

The following item requires an illumination:
EMZ-5 + MA502 + F + S-4100 Binocular
EMZ-13 + MA502 + FS + S-4300 Binocular

  • EMZ-13 + MA502 + FS + S-4300, Stereo Zoom Binocular Stand Configuration System, Magnification (10X – 70X), W.D. 90mm (3.54″)

  • EMZ-5H + MA522 + F + S-1100, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-5 + MA502 + F + S-4100, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-13TR + MA502 + F + S-4100 + MA961D/S/ESD + MA151/35/03 + HD1500TM, Stereo Zoom Trinocular Stand Configuration System, Magnification (1.0X – 7.0X), W.D. 90mm (3.54″)

The following item requires an illumination:
EMZ-5 + MA502 + F + FA-4 Binocular

  • EMZ-13 + MA502 + FSC + SAS-3, Stereo Zoom Binocular Stand Configuration System, Magnification (10X – 70X), W.D. 90mm (3.54″)

  • EMZ-5 + MA502 + F + FA-4, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-5TRH + MA522 + CR-2, Stereo Zoom Trinocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-5TRH + MA522 + F + FA-4, Stereo Zoom Trinocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

The following item requires an illumination:
EMZ-5 + MA502 + F + BAS-2 Binocular
EMZ-13 + MA502 + F + BAS-2

  • EMZ-5 + MA502 + F + BAS-2, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-13 + MA502 + F + BAS-2, Stereo Zoom Binocular Stand Configuration System, Magnification (10X – 70X), W.D. 90mm (3.54″)

  • EMZ-8TRD + MA502 + FSC + BAS-3, Stereo Zoom Trinocular Stand Configuration System, Magnification (0.7X-0.45X), W.D. 104mm (4.1″)

  • EMZ-5H/BLACK + MA522 + F + BAS-2, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EM-33 LED Trinocular Entry-Level 0.7X-4.5X Incident and Transmitted Zoom Stereo Microscope

  • EM-31 LED Binocular Entry-Level Dual 2x, 4x Incident and Transmitted Turret Stereo Microscope

  • EM-30 LED Binocular Entry-Level Dual 1x,3x Incident and Transmitted Turret Stereo Microscope

  • EM-32 LED Binocular Entry-Level 0.7X-4.5X Incident and Transmitted Zoom Stereo Microscope

  • EM-50L Binocular Stereo Entry-Level Industrial and Educational Microscope with 6.7X – 45X Zoom Range Magnification on a pole stand with 58 bulb array LED Ring Light (MA962) and Ring Light adapter

  • EM-51L Trinocular Stereo Entry-Level Industrial and Educational Microscope with 6.7X – 45X Zoom Range Magnification on a pole stand

  • EM-22 LED Binocular Entry-Level 1X, 2X, 3X Incident and Transmitted Turret Stereo Rechargeable Microscope

  • SKT-2BT/LED Binocular Entry-Level Microscope (1X and 3X Turret) (Limited Supply Available)

  • EM-23 LED Binocular Entry-Level 1X, 2X, 4X Incident and Transmitted Turret Stereo Rechargeable Microscope

  • EM-20 LED Binocular Entry-Level 1X, 3X Incident and Transmitted Turret Stereo Rechargeable Microscope

  • EM-21 LED Binocular Entry-Level 2X, 4X Incident and Transmitted Turret Stereo Rechargeable Microscope

  • MT5200L LED Binocular Brightfield Biological Microscope

  • MT5200H Halogen Binocular Brightfield Research/Clinical Studies Biological Microscope

  • MT5300H Halogen Trinocular Brightfield Biological Microscope

  • MT4200L Biological Compound Binocular Brightfield with Infinity Corrected U.Plan Objectives (4X, 10X, 40X, 100X Oil), LED Illumination – Magnification Range: 40X–1000X

  • MT4300L 40X-1000X Biological Compound Binocular Brightfield with Infinity Corrected U. Plan 4X, 10X, 40X, 100X, LED

  • MT4310L – 40X-400X Biological Compound Trinocular Brightfield/Phase Contrast with Infinity Corrected with 4X BF, 10X PH, 40X PH LED

  • MT4210H – 40X-400X Brightfield/Phase Contrast Biological Compound Binocular with Infinity Corrected 4X BF, 10X PH, 40X PH Halogen

  • MT4310H 40X-400X Biological Compound Ergoomic Trino Brightfield/Phase Contrast with Infinity Corrected 4X BF, 10X PH, 40X PH, Halogen

  • MT5310L LED Trinocular Brightfield/Phase Contrast Biological Microscope

  • MT4310L + HD1500TM + MA151/35/03, 40X-400X Biological Compound Trinocular Brightfield/Phase Contrast with Infinity Corrected with 4X BF, 10X PH, 40X PH LED with HD Camera Monitor (HD1500TM)

  • MT4300L + HD1500MET + MA151/35/03 LED 40X-1000X Biological Compound Binocular Brightfield with Infinity Corrected U. Plan 4X, 10X, 40X, 100X, LED with HD Camera Measurement (HD1500MET)

  • TC-5100H – Biological Inverted Binocular Brightfield Compound Microscope with Transmitted Halogen Illuminator and Infinity TC LWD Planachromat Objectives 10X and 20X

  • TC-5300L Binocular Inverted Brightfield/Phase Contrast Biological Microscope with LED illumination

  • TC-5300EL 100X, 200X Binocular Inverted Brightfield/Phase Contrast Biological Microscope with LED illumination

  • TC-5400L Binocular Inverted Brightfield/Phase Contrast Biological Microscope with LED Illumination

  • TC-5400-HD1500TM/0.3 100X, 200X Trinocular Inverted Brightfield/Phase Contrast Biological Microscope and HD Camera (HD1500TM)

  • TC-5200H – Biological Inverted Brightfield Trinocular Compound Microscope with Transmitted Halogen Illuminator and Infinity TC LWD Planachromat Objectives 10X and 20X

  • MT6200CL Binocular Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6200ECL Ergonomic Tilting Binocular 10° to 50° degrees Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300CL Trinocular Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300CLM Motorized Fluorescence Microscope

  • MT6200ECW Ergonomic Tilting Binocular 10° to 50° degrees Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300CW Trinocular Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300ECL Ergonomic Tilting Trinocular 10° to 50° degrees Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6200CW Binocular Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300ECW Ergonomic Tilting Binocular 10° to 50° degrees Epi-Fluorescence Biological Microscope with LED Light Source

  • TC-5500CL 100X, 200X Binocular LED/Halogen Inverted Epi-Fluorescence Biological Microscope

  • TC-5600CL Trinocular Inverted LED/Halogen Epi-Fluorescence Biological Microscope

  • TC-5500CW 100X, 200X Binocular LED/Halogen Inverted Epi-Fluorescence Biological Microscope

  • TC-5600CW Trinocular Inverted LED/Halogen Epi-Fluorescence Biological Microscope

  • MT4200L Biological Compound Binocular Brightfield with Infinity Corrected U.Plan Objectives (4X, 10X, 40X, 100X Oil), LED Illumination – Magnification Range: 40X–1000X

  • MT4300L 40X-1000X Biological Compound Binocular Brightfield with Infinity Corrected U. Plan 4X, 10X, 40X, 100X, LED

  • MT-51 Research Grade Trinocular Brightfield Upright Biological Compound Microscope with Advanced S.Plan 4X, 10X, 40X, 100X and LED Illumination

  • MT-50 Research Grade Binocular Brightfield Upright Biological Compound Microscope with Advanced S.Plan 4X, 10X, 40X, 100X and LED Illumination

  • MT-61 Trinocular Brightfield Upright Biological Compound Microscope with Infinity – Corrected Plan 4X, 10X, 40X, 100Xoil and LED Illumination

  • MT-60 Binocular Brightfield Upright Biological Compound Microscope with Infinity-Corrected Plan 4X, 10X, 40X, 100Xoil and LED Illumination

  • MT4210H – 40X-400X Brightfield/Phase Contrast Biological Compound Binocular with Infinity Corrected 4X BF, 10X PH, 40X PH Halogen

  • MT4310H 40X-400X Biological Compound Ergoomic Trino Brightfield/Phase Contrast with Infinity Corrected 4X BF, 10X PH, 40X PH, Halogen

  • MTA/MT-53 Research Grade Trinocular Brightfield Upright Biological Compound Microscope with Advanced Phase Contrast Plan Phase PH10x, PH20x, PH40x PH100x Oil and LED Illumination


Histopathology

UNIVERSITY

The following item requires an illumination:
EMZ-5 + MA502 + P Stand

  • EMZ-5 + MA502 + P, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-5 + MA502 + PKL-2, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-13 + MA502 + PLS-2, Stereo Zoom Binocular Stand Configuration System, Magnification (10X – 70X), W.D. 90mm (3.54″)

  • CZ-1105 1X CMO Binocular Zoom Stereo System, Working Distance 78mm

  • CZ-1105TR 1X CMO Trinocular Zoom Stereo System, Working Distance 78mm

  • CZ-1100 1X CMO Ergonomic Binocular Zoom Stereo System, Working Distance 78mm

  • CZ-1100TR 1X CMO Ergonomic Trinocular Zoom Stereo System, Working Distance 78mm

The following item requires an illumination:
EMZ-5 + MA502 + F + S-4100 Binocular
EMZ-13 + MA502 + FS + S-4300 Binocular

  • EMZ-13 + MA502 + FS + S-4300, Stereo Zoom Binocular Stand Configuration System, Magnification (10X – 70X), W.D. 90mm (3.54″)

  • EMZ-5H + MA522 + F + S-1100, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-5 + MA502 + F + S-4100, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-13TR + MA502 + F + S-4100 + MA961D/S/ESD + MA151/35/03 + HD1500TM, Stereo Zoom Trinocular Stand Configuration System, Magnification (1.0X – 7.0X), W.D. 90mm (3.54″)

The following item requires an illumination:
EMZ-5 + MA502 + F + FA-4 Binocular

  • EMZ-13 + MA502 + FSC + SAS-3, Stereo Zoom Binocular Stand Configuration System, Magnification (10X – 70X), W.D. 90mm (3.54″)

  • EMZ-5 + MA502 + F + FA-4, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-5TRH + MA522 + CR-2, Stereo Zoom Trinocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-5TRH + MA522 + F + FA-4, Stereo Zoom Trinocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

The following item requires an illumination:
EMZ-5 + MA502 + F + BAS-2 Binocular
EMZ-13 + MA502 + F + BAS-2

  • EMZ-5 + MA502 + F + BAS-2, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EMZ-13 + MA502 + F + BAS-2, Stereo Zoom Binocular Stand Configuration System, Magnification (10X – 70X), W.D. 90mm (3.54″)

  • EMZ-8TRD + MA502 + FSC + BAS-3, Stereo Zoom Trinocular Stand Configuration System, Magnification (0.7X-0.45X), W.D. 104mm (4.1″)

  • EMZ-5H/BLACK + MA522 + F + BAS-2, Stereo Zoom Binocular Stand Configuration System, Magnification (7X – 45X), W.D. 93mm (3.66″)

  • EM-33 LED Trinocular Entry-Level 0.7X-4.5X Incident and Transmitted Zoom Stereo Microscope

  • EM-31 LED Binocular Entry-Level Dual 2x, 4x Incident and Transmitted Turret Stereo Microscope

  • EM-30 LED Binocular Entry-Level Dual 1x,3x Incident and Transmitted Turret Stereo Microscope

  • EM-32 LED Binocular Entry-Level 0.7X-4.5X Incident and Transmitted Zoom Stereo Microscope

  • EM-50L Binocular Stereo Entry-Level Industrial and Educational Microscope with 6.7X – 45X Zoom Range Magnification on a pole stand with 58 bulb array LED Ring Light (MA962) and Ring Light adapter

  • EM-51L Trinocular Stereo Entry-Level Industrial and Educational Microscope with 6.7X – 45X Zoom Range Magnification on a pole stand

  • MT5200L LED Binocular Brightfield Biological Microscope

  • MT5200H Halogen Binocular Brightfield Research/Clinical Studies Biological Microscope

  • MT5300H Halogen Trinocular Brightfield Biological Microscope

  • MT4200L Biological Compound Binocular Brightfield with Infinity Corrected U.Plan Objectives (4X, 10X, 40X, 100X Oil), LED Illumination – Magnification Range: 40X–1000X

  • MT4300L 40X-1000X Biological Compound Binocular Brightfield with Infinity Corrected U. Plan 4X, 10X, 40X, 100X, LED

  • MT4310L – 40X-400X Biological Compound Trinocular Brightfield/Phase Contrast with Infinity Corrected with 4X BF, 10X PH, 40X PH LED

  • MT4210H – 40X-400X Brightfield/Phase Contrast Biological Compound Binocular with Infinity Corrected 4X BF, 10X PH, 40X PH Halogen

  • MT4310H 40X-400X Biological Compound Ergoomic Trino Brightfield/Phase Contrast with Infinity Corrected 4X BF, 10X PH, 40X PH, Halogen

  • MT5310L LED Trinocular Brightfield/Phase Contrast Biological Microscope

  • MT4310L + HD1500TM + MA151/35/03, 40X-400X Biological Compound Trinocular Brightfield/Phase Contrast with Infinity Corrected with 4X BF, 10X PH, 40X PH LED with HD Camera Monitor (HD1500TM)

  • MT4300L + HD1500MET + MA151/35/03 LED 40X-1000X Biological Compound Binocular Brightfield with Infinity Corrected U. Plan 4X, 10X, 40X, 100X, LED with HD Camera Measurement (HD1500MET)

  • TC-5100H – Biological Inverted Binocular Brightfield Compound Microscope with Transmitted Halogen Illuminator and Infinity TC LWD Planachromat Objectives 10X and 20X

  • TC-5300L Binocular Inverted Brightfield/Phase Contrast Biological Microscope with LED illumination

  • TC-5300EL 100X, 200X Binocular Inverted Brightfield/Phase Contrast Biological Microscope with LED illumination

  • TC-5400L Binocular Inverted Brightfield/Phase Contrast Biological Microscope with LED Illumination

  • TC-5400-HD1500TM/0.3 100X, 200X Trinocular Inverted Brightfield/Phase Contrast Biological Microscope and HD Camera (HD1500TM)

  • TC-5200H – Biological Inverted Brightfield Trinocular Compound Microscope with Transmitted Halogen Illuminator and Infinity TC LWD Planachromat Objectives 10X and 20X

  • MT6200CL Binocular Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6200ECL Ergonomic Tilting Binocular 10° to 50° degrees Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300CL Trinocular Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300CLM Motorized Fluorescence Microscope

  • MT6200ECW Ergonomic Tilting Binocular 10° to 50° degrees Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300CW Trinocular Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300ECL Ergonomic Tilting Trinocular 10° to 50° degrees Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6200CW Binocular Epi-Fluorescence Biological Microscope with LED Light Source

  • MT6300ECW Ergonomic Tilting Binocular 10° to 50° degrees Epi-Fluorescence Biological Microscope with LED Light Source

  • TC-5500CL 100X, 200X Binocular LED/Halogen Inverted Epi-Fluorescence Biological Microscope

  • TC-5600CL Trinocular Inverted LED/Halogen Epi-Fluorescence Biological Microscope

  • TC-5500CW 100X, 200X Binocular LED/Halogen Inverted Epi-Fluorescence Biological Microscope

  • TC-5600CW Trinocular Inverted LED/Halogen Epi-Fluorescence Biological Microscope

  • MT4200L Biological Compound Binocular Brightfield with Infinity Corrected U.Plan Objectives (4X, 10X, 40X, 100X Oil), LED Illumination – Magnification Range: 40X–1000X

  • MT4300L 40X-1000X Biological Compound Binocular Brightfield with Infinity Corrected U. Plan 4X, 10X, 40X, 100X, LED

  • MT-51 Research Grade Trinocular Brightfield Upright Biological Compound Microscope with Advanced S.Plan 4X, 10X, 40X, 100X and LED Illumination

  • MT-50 Research Grade Binocular Brightfield Upright Biological Compound Microscope with Advanced S.Plan 4X, 10X, 40X, 100X and LED Illumination

  • MT-61 Trinocular Brightfield Upright Biological Compound Microscope with Infinity – Corrected Plan 4X, 10X, 40X, 100Xoil and LED Illumination

  • MT-60 Binocular Brightfield Upright Biological Compound Microscope with Infinity-Corrected Plan 4X, 10X, 40X, 100Xoil and LED Illumination

  • MT4210H – 40X-400X Brightfield/Phase Contrast Biological Compound Binocular with Infinity Corrected 4X BF, 10X PH, 40X PH Halogen

  • MT4310H 40X-400X Biological Compound Ergoomic Trino Brightfield/Phase Contrast with Infinity Corrected 4X BF, 10X PH, 40X PH, Halogen

  • MTA/MT-53 Research Grade Trinocular Brightfield Upright Biological Compound Microscope with Advanced Phase Contrast Plan Phase PH10x, PH20x, PH40x PH100x Oil and LED Illumination